An advanced plant stem cell serum with Edelweiss and Swiss Apple meristem cell cultures, Ectoin, and a peptide complex that revitalizes skin, improves firmness, and supports anti-aging performance at the cellular level.
Plant stem cells represent a different category of anti-aging active than peptides or retinoids. Where those work by stimulating specific cell functions, meristem cell cultures work by supporting the vitality and longevity of the skin's own stem cells, the cells responsible for producing new, healthy skin. The Circadia MeriStem Antioxidant Serum combines two distinct plant meristem extracts, Edelweiss and Swiss Apple, with Ectoin and a peptide complex to deliver advanced cellular protection and rejuvenation in a lightweight, twice-daily serum that even sensitive skin can tolerate.
Expanded Description
Skin aging operates at two levels that most anti-aging products address separately. Structural aging, the visible loss of firmness and the deepening of lines, is the downstream result of cellular aging: the gradual decline in the skin's stem cell population and the capacity of those cells to produce new, healthy epidermis. Products that only address the structural level can temporarily improve appearance but don't slow the underlying process. The Circadia MeriStem Antioxidant Serum approaches both.
The formula is built on two complementary plant meristem cell cultures. Leontopodium Alpinum (Edelweiss) Meristem Cell Culture is derived from the Alpine Edelweiss plant, one of the most UV-resistant and stress-tolerant plants in the world. Its meristem culture captures the plant's own cellular protective mechanisms, which include some of the most potent natural antioxidant and UV-protective compounds found in any botanical. When applied to skin, it helps the skin's own cells resist UV-induced oxidative damage and delay the cellular senescence that accelerates structural aging.
Malus Domestica (Swiss Apple) Fruit Cell Culture Extract is derived from the Uttwiler Spätlauber, a Swiss apple variety historically notable for its exceptional storage longevity, even after harvest. Its meristem culture has been studied for its ability to maintain the vitality and self-renewal capacity of human stem cells, delaying senescence and supporting the production of new, healthy skin cells over time.
Ectoin is a natural compound originally isolated from extremophile bacteria that survive in extreme environmental conditions. In skincare, it creates a hydration shell around proteins and cell membranes, stabilizing cellular structures against heat, UV, and osmotic stress. It has clinical data supporting its role in reducing UV-induced DNA damage and supporting the skin's own repair processes.
Cyclotetrapeptide-24 Aminocyclohexane Carboxylate is a peptide complex that addresses skin neuro-responses, specifically reducing the release of catecholamines (stress hormones) at the skin level that contribute to accelerated visible aging under stress.
Aloe Barbadensis Leaf Juice provides the formula's hydrating and soothing base. The serum is lightweight, non-comedogenic, and suitable for twice-daily use. Particularly well-suited to sensitive skin that cannot tolerate more aggressive actives, or as a supportive layer in a routine that already includes retinoids or acids.
The formula is built on two complementary plant meristem cell cultures. Leontopodium Alpinum (Edelweiss) Meristem Cell Culture is derived from the Alpine Edelweiss plant, one of the most UV-resistant and stress-tolerant plants in the world. Its meristem culture captures the plant's own cellular protective mechanisms, which include some of the most potent natural antioxidant and UV-protective compounds found in any botanical. When applied to skin, it helps the skin's own cells resist UV-induced oxidative damage and delay the cellular senescence that accelerates structural aging.
Malus Domestica (Swiss Apple) Fruit Cell Culture Extract is derived from the Uttwiler Spätlauber, a Swiss apple variety historically notable for its exceptional storage longevity, even after harvest. Its meristem culture has been studied for its ability to maintain the vitality and self-renewal capacity of human stem cells, delaying senescence and supporting the production of new, healthy skin cells over time.
Ectoin is a natural compound originally isolated from extremophile bacteria that survive in extreme environmental conditions. In skincare, it creates a hydration shell around proteins and cell membranes, stabilizing cellular structures against heat, UV, and osmotic stress. It has clinical data supporting its role in reducing UV-induced DNA damage and supporting the skin's own repair processes.
Cyclotetrapeptide-24 Aminocyclohexane Carboxylate is a peptide complex that addresses skin neuro-responses, specifically reducing the release of catecholamines (stress hormones) at the skin level that contribute to accelerated visible aging under stress.
Aloe Barbadensis Leaf Juice provides the formula's hydrating and soothing base. The serum is lightweight, non-comedogenic, and suitable for twice-daily use. Particularly well-suited to sensitive skin that cannot tolerate more aggressive actives, or as a supportive layer in a routine that already includes retinoids or acids.
Headline
An advanced plant stem cell serum with Edelweiss and Swiss Apple meristem cell cultures, Ectoin, and a peptide complex that revitalizes skin, improves firmness, and supports anti-aging performance at the cellular level.
Skin Concern
Cellular Aging, Loss of Firmness, Dullness, Fine Lines, UV Damage, Oxidative Stress, Sensitive Skin
Perfect For
All Skin Types including Sensitive. Especially beneficial for aging and mature skin, those who cannot tolerate retinol or acids, and anyone looking to support cellular-level anti-aging alongside a standard regimen.
Product Size
0.5 fl oz / 15mL | Lightweight Serum
How To Use
• Morning and evening, after cleansing, apply several drops to fingertips.
• Smooth gently over face and neck.
• Allow to absorb fully before applying moisturizer.
• For best results, follow with PhiTo-Pep 1.6 Antioxidant Lotion in the PM routine.
• Avoid contact with eyes.
• Smooth gently over face and neck.
• Allow to absorb fully before applying moisturizer.
• For best results, follow with PhiTo-Pep 1.6 Antioxidant Lotion in the PM routine.
• Avoid contact with eyes.
Pro Tip
Layer MeriStem under PhiTo-Pep 1.6 in the evening for a combined stem cell and advanced peptide anti-aging routine. MeriStem addresses the cellular level; PhiTo-Pep addresses the structural level. Together they deliver a more complete anti-aging protocol than either does alone.
Ingredients
Edelweiss Meristem Cell Culture (Leontopodium Alpinum Meristem Cell Culture): Derived from one of the world's most UV and stress-resistant plants, this extract captures exceptional antioxidant and cellular protection capacity that helps skin resist UV-induced damage and delayed cellular aging.
Swiss Apple Stem Cell Extract (Malus Domestica Fruit Cell Culture Extract): Supports the vitality and self-renewal capacity of skin stem cells, delaying senescence and promoting the production of new healthy skin.
Ectoin: A natural extremophile-derived compound that forms a protective hydration shell around cellular structures, reducing UV-induced DNA damage and supporting the skin's own repair processes.
Cyclotetrapeptide-24 Aminocyclohexane Carboxylate: A peptide complex that reduces stress-hormone release at the skin level, addressing a specific neuro-aging pathway that contributes to visible aging under stress.
Aloe Barbadensis Leaf Juice: Provides soothing, healing, and hydrating support as the formula's base.
Full Ingredient List: Aqua/Water, Citric Acid, Pentylene Glycol, Aloe Barbadensis Leaf Juice, Xanthan Gum, Ammonium Acryloyldimethyltaurate/VP Copolymer, Caprylyl Glycol, Leontopodium Alpinum Meristem Cell Culture, Alcohol, Phenoxyethanol, Tetrasodium EDTA, Malus Domestica Fruit Cell Culture Extract, Hexylene Glycol, Ectoin, Lecithin, Glycerin, Sodium Hydroxide, Sodium Metabisulfite, Sodium Benzoate, Potassium Sorbate, Cyclotetrapeptide-24 Aminocyclohexane Carboxylate.
Swiss Apple Stem Cell Extract (Malus Domestica Fruit Cell Culture Extract): Supports the vitality and self-renewal capacity of skin stem cells, delaying senescence and promoting the production of new healthy skin.
Ectoin: A natural extremophile-derived compound that forms a protective hydration shell around cellular structures, reducing UV-induced DNA damage and supporting the skin's own repair processes.
Cyclotetrapeptide-24 Aminocyclohexane Carboxylate: A peptide complex that reduces stress-hormone release at the skin level, addressing a specific neuro-aging pathway that contributes to visible aging under stress.
Aloe Barbadensis Leaf Juice: Provides soothing, healing, and hydrating support as the formula's base.
Full Ingredient List: Aqua/Water, Citric Acid, Pentylene Glycol, Aloe Barbadensis Leaf Juice, Xanthan Gum, Ammonium Acryloyldimethyltaurate/VP Copolymer, Caprylyl Glycol, Leontopodium Alpinum Meristem Cell Culture, Alcohol, Phenoxyethanol, Tetrasodium EDTA, Malus Domestica Fruit Cell Culture Extract, Hexylene Glycol, Ectoin, Lecithin, Glycerin, Sodium Hydroxide, Sodium Metabisulfite, Sodium Benzoate, Potassium Sorbate, Cyclotetrapeptide-24 Aminocyclohexane Carboxylate.
